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. Author manuscript; available in PMC: 2022 Dec 6.
Published in final edited form as: Neurosci Biobehav Rev. 2022 Sep 26;142:104884. doi: 10.1016/j.neubiorev.2022.104884

Figure 1.

Figure 1.

General procedures and outcomes for stress enhancement of fear learning (SEFL). Stress-induction: mice or rats receive repeated or no footshocks in context A. Single-trial fear conditioning: the next day (or weeks later) all subjects, receive a single footshock after a few minutes in a novel context B, and 24 hrs later are returned to context B to assess freezing. As depicted in the simulated bar graph, the group previously exposed to stress exhibits greater freezing than the non-stressed group in context B.