| Early or late |
| Major |
4.60 (2.51-8.43) |
94% |
5 |
| Major, excluding outliers |
3.43 (2.68-4.40) |
0% |
2 |
| Major or minor |
4.25 (3.40-5.32) |
0% |
3 |
| Combined |
4.44 (3.02-6.52) |
89% |
8 |
| Combined, excluding outliers |
3.86 (3.27-4.56) |
0% |
5 |
| Minor |
2.73 (2.07-3.61) |
0% |
2 |
| Early |
| Major |
3.42 (2.48-4.12) |
0% |
4 |
| Major or minor |
4.65 (3.54-6.11) |
0% |
3 |
| Combined |
3.77 (3.23-4.41) |
1% |
7 |
| Late |
| Major |
7.92 (3.80-16.51) |
91% |
3 |
| Major, excluding outliers |
5.62 (4.37-7.22) |
0% |
2 |
| Major or minor |
4.43 (2.28-8.63) |
94% |
5 |
| Major or minor, excluding outliers |
5.62 (4.59-6.87) |
0% |
4 |
| Combined |
5.51 (3.13-9.68) |
95% |
8 |
| Combined, excluding outliers |
5.62 (4.80-6.57) |
0% |
6 |
| Minor |
2.11 (1.53-2.90) |
43% |
4 |
| Myocardial infarction |
| Early or late |
4.11 (3.34-5.03) |
58% |
8 |
| Early or late, excluding outliers |
4.13 (3.54-4.82) |
8% |
6 |
| Early |
2.45 (1.98-3.02) |
25% |
7 |
| Late |
4.67 (2.85-7.63) |
94% |
8 |
| Late, excluding outliers |
6.19 (4.86-7.89) |
53% |
6 |
| Bleeding vs myocardial infarction |
| Early or late |
| Major |
1.23 (0.62-2.47) |
89% |
5 |
| Major, excluding outliers |
1.13 (0.72-1.78) |
57% |
3 |
| Major or minor |
0.91 (0.65-1.27) |
0% |
3 |
| Combined |
1.10 (0.71-1.71) |
81% |
8 |
| Combined, excluding outliers |
1.03 (0.80-1.32) |
19% |
6 |
| Minor |
0.62 (0.42-0.92) |
0% |
2 |
| Early |
| Major |
1.28 (0.97-1.68) |
0% |
4 |
| Major or minor |
2.06 (1.27-3.35) |
0% |
3 |
| Combined |
1.46 (1.13-1.89) |
7% |
7 |
| Late |
| Major |
1.28 (0.93-1.76) |
12% |
3 |
| Major or minor |
1.04 (0.70-1.54) |
61% |
5 |
| Major or minor, excluding outliers |
0.86 (0.69-1.07) |
0% |
4 |
| Combined |
1.14 (0.87-1.49) |
53% |
8 |
| Combined, excluding outliers |
1.10 (0.82-1.24) |
16% |
7 |
| Minor |
0.35 (0.25-0.49) |
19% |
4 |
| Outliers were identified by visual inspection of Galbraith plots, which are reported in Supplementary Figure 2-Supplementary Figure 24. CI: confidence interval; HR: hazard ratio |
