| Age, years |
69 (60-78) |
70 (60-79) |
68 (60-77) |
0.20 |
| Male sex |
477 (76.2%) |
213 (79.2%) |
264 (73.9%) |
0.13 |
| Body mass index, kg/m² |
26.7 (24.5-29.4) |
26.8 (24.2-29.4) |
26.6 (24.7-29.4) |
0.40 |
| Cardiovascular risk factors |
Current smoking |
165/608 (27.1%) |
68/266 (25.6%) |
97/342 (28.4%) |
0.44 |
| Hypertension |
369/621 (59.4%) |
157/268 (58.6%) |
212/353 (60.1%) |
0.71 |
| Hypercholesterolaemia |
200/619 (32.3%) |
88/268 (32.8%) |
112/351 (31.9%) |
0.81 |
| Diabetes mellitus |
192/619 (31.0%) |
94/268 (35.1%) |
98/351 (27.9%) |
0.06 |
| Prior myocardial infarction |
97/623 (15.6%) |
44/268 (16.4%) |
53/355 (14.9%) |
0.61 |
| Prior stroke |
40/624 (6.4%) |
23/269 (8.6%) |
17/355 (4.8%) |
0.06 |
| Prior peripheral artery disease |
70/625 (11.2%) |
39/269 (14.5%) |
31/356 (8.7%) |
0.02 |
| Prior percutaneous coronary intervention |
105/623 (16.9%) |
41/268 (15.3%) |
64/355 (18.0%) |
0.37 |
| Resuscitation before randomisation |
328/625 (52.5%) |
127/268 (47.4%) |
201/357 (56.3%) |
0.03 |
| Fibrinolysis <24 hrs before randomisation |
32/624 (5.1%) |
12/268 (4.5%) |
20/356 (5.6%) |
0.52 |
| ST-segment elevation myocardial infarction |
392/608 (64.5%) |
165/261 (63.2%) |
227/347 (65.4%) |
0.58 |
| Left bundle branch block |
86/609 (14.1%) |
38/261 (14.6%) |
48/348 (13.8%) |
0.79 |
| Heart rate, beats/min |
90.0 (72.0-107.0) |
96.0 (79.0-110.0) |
87.0 (67.0-104.0) |
<0.001 |
| Systolic blood pressure, mmHg |
100.0 (85.0-125.0) |
101.0 (84.0-125.0) |
100.0 (86.0-125.0) |
0.82 |
| Diastolic blood pressure, mmHg |
60.0 (50.0-80.0) |
62.5 (50.0-80.0) |
60.0 (50.0-80.0) |
0.99 |
| Mean blood pressure, mmHg |
76.0 (63.3-93.3) |
76.7 (63.3-93.3) |
75.7 (63.3-93.3) |
0.94 |
| Arterial lactate >2.0 mmol/L |
403/610 (66.1%) |
173/265 (65.3%) |
230/345 (66.7%) |
0.72 |
| Number of affected vessels |
1 |
5/626 (0.8%) |
1/269 (0.4%) |
4/357 (1.1%) |
0.32 |
| 2 |
232/626 (37.1%) |
93/269 (34.6%) |
139/357 (38.9%) |
| 3 |
389/626 (62.1%) |
175/269 (65.1%) |
214/357 (59.9%) |
| ≥1 chronic total occlusion* |
132/626 (21.1%) |
69/269 (25.7%) |
63/357 (17.6%) |
0.015 |
| Pre-PCI SYNTAX score* |
Low SYNTAX score |
261/617 (42.3%) |
66/263 (25.1%) |
195/354 (55.1%) |
<0.001 |
| Intermediate SYNTAX score |
204/617 (33.1%) |
106/263 (40.3%) |
98/354 (27.7%) |
| High SYNTAX score |
152/617 (24.6%) |
91/263 (34.6%) |
61/354 (17.2%) |
| Left ventricular ejection fraction§
|
31.0 (25.0-40.0) |
30.0 (20.0-40.0) |
35.0 (28.0-45.0) |
<0.001 |
| *according to core laboratory data. § available in 238 patients. PCI: percutaneous coronary intervention; SYNTAX score: Synergy between PCI with Taxus drug-eluting stent and cardiac surgery score |
