Table 2. Relationships of P2-HNF4α, p-STAT3 and c-Myc expression in liver biopsies and components of the metabolic syndrome and liver fibrosis.
P2-HNF4α | p-STAT3 | c-Myc | |||||||
---|---|---|---|---|---|---|---|---|---|
Groups | + | − | p | + | − | p | + | − | p |
Obese | 24 | 15 | NS | 5 | 34 | NS | 5 | 34 | NS |
Not obese | 4 | 6 | 1 | 9 | 0 | 10 | |||
Hypertensive | 17 | 13 | NS | 6 | 24 | 0.037 | 5 | 25 | 0.06 |
Normotensive | 11 | 8 | 0 | 19 | 0 | 19 | |||
Diabetic | 12 | 13 | NS | 3 | 22 | NS | 3 | 22 | NS |
Not diabetic* | 15 | 5 | 2 | 18 | 0 | 22 | |||
FS** 3–4 | 4 | 5 | NS | 2 | 7 | NS | 3 | 6 | 0.011 |
FS 0–2 | 24 | 16 | 4 | 36 | 2 | 38 |
* Diabetes status was unknown on four patients. Abbreviation: ** FS: Fibrosis stage.