Table 3.
Laboratory and chest findings on admission of the mild to moderate Patients with SARS-CoV-2 Omicron based on neurological manifestations.
| Items | With neurological manifestations |
Without neurological manifestations |
Univariate regression |
Multivariate regressiona |
||
|---|---|---|---|---|---|---|
| ( n = 169) | ( n = 182) | B (95 %CI) | p-value | B (95 %CI) | p-value | |
| Blood test, median(25th, 75th) | ||||||
| WBC count, *10^9/L | 5.20(3.83, 6.30) | 5.10(4.00, 6.20) | -0.004(0.887, 1.118) | 0.947 | -0.006(0.880, 1.124) | 0.929 |
| Monocyte cell count, *10^9/L | 0.52(0.39, 0.68) | 0.49(0.41, 0.68) | -0.196(0.391, 1.729) | 0.605 | -0.022(0.452, 2.119) | 0.956 |
| Lymphocyte count, *10^9/L | 1.35(1.00, 1.80) | 1.30(1.00, 2.00) | 0.274(0.904, 1.913) | 0.152 | 0.056(0.708, 1.580) | 0.786 |
| Neutrophil, % | 58.25(49.93, 66.58) | 59.40(41.86, 68.40) | -0.005(0.979, 1.011) | 0.534 | 0.000(0.983, 1.017) | 0.982 |
| Hemoglobin, g/L | 131.00(123.25, 142.00) | 128.00(116.00, 141.00) | 0.012(0.999, 1.024) | 0.062 | 0.012(0.997, 1.026) | 0.114 |
| Platelet count, *10^9/L | 189.00(154.00, 231.50) | 174.00(138.00, 230.00) | 0.003(1.000, 1.006) | 0.081 | 0.001(0.998, 1.004) | 0.552 |
| C-reactive protein, mg/L | 3.86(1.69, 7.49) | 4.76(1.61, 15.46) | -0.024(0.958, 0.995) | 0.013* | -0.016(0.996, 1.002) | 0.083 |
| TBil, mmol/L | 10.40(8.25, 13.85) | 10.00(8.00, 12.90) | 0.013(0.997, 1.052) | 0.476 | 0.028(0.988, 1.070) | 0.174 |
| Albumin, g/L | 40.00(38.00, 43.00) | 39.00(37.00, 43.00) | 0.071(1.019,1.131) | 0.008** | 0.032(0.974, 1.094) | 0.286 |
| D-dimer, mg/L | 0.36(0.19, 0.73)) | 0.46(0.25, 0.90) | -0.202(0.639, 1.044) | 0.106 | -0.053(0.729, 1.238) | 0.699 |
| PT, s | 10.80(10.40, 11.30) | 11.00(10.50, 11.40) | -0.023(0.920, 1.038) | 0.449 | -0.014(0.941, 1.033) | 0.558 |
| Fibrinogen, g/L | 2.92(2.53, 3.52) | 3.10(2.62, 3.68) | -0.021(0.922, 1.040) | 0.492 | 0.022(0.985, 1.092) | 0.506 |
| APTT, s | 28.50(26.70, 30.20) | 28.60(26.50, 30.80) | -0.021(0.922, 1.040) | 0.492 | 0.022(0.958, 1.092) | 0.506 |
| Creatine kinase, U/L | 81.50(57.25, 108.75) | 95.50(64.00, 139.00) | -0.004(0.994, 0.999) | 0.005** | -0.003(0.995, 1.000) | 0.039* |
| Lactate dehydrogenase, U/L | 203.00(175.5, 229.75) | 210.50(188.75, 238.00) | -0.006(0.988, 1.000) | 0.058 | -0.005(0.989, 1.002) | 0.146 |
| Myohemoglobin, μg/L | 24.30(16.55, 35.70) | 36.35(24.10, 54.08) | -0.023(0.967, 0.988) | <0.001*** | -0.016(0.974, 0.996) | 0.006** |
| Chest CT findings,n(%) | ||||||
| Bilateral lung involvement | 69(40.8) | 72(39.6) | 0.053(0.688, 1.616) | 0.809 | 0.272(0.827, 2.083) | 0.249 |
| Patchy shadowing | 84(49.7) | 79(43.4) | 0.253(0.846, 1.962) | 0.238 | 0.497(1.048, 2.577) | 0.030* |
| Effusion shadowing | 3(1.8) | 17(9.3) | -1.741(0.050, 0.610) | 0.006** | -1.268(0.077, 1.025) | 0.054 |
| Ground-glass opacity | 10(5.9) | 12(6.6) | -0.115(0.375, 2.120) | 0.794 | -0.270(0.310, 1.879) | 0.557 |
| Interstitial abnormalities | 13(7.7) | 18(9.9) | -0.275(0.360, 1.601) | 0.469 | -0.025(0.450, 2.113) | 0.949 |
| Consolidation | 3(1.8) | 8(4.4) | -0.934(0.103, 1.507) | 0.173 | -0.540(0.142, 2.390) | 0.453 |
Abbreviation: WBC, White blood cell; TBil, total bilirubin; PT, prothrombin time; APTT, activated partial thromboplastin time.
Note: CI, confidence interval; *, p < 0.05; **, p < 0.01; ***, p < 0.001; a, confounding factors(age, gender and anticoagulation) from Table 1 were entered into the logistic regression analysis model.