Table 2.
Laboratory investigations of patients with chronic spontaneous urticaria (CSU) with positive and negative antinuclear antibodies (ANA).
| Patients with CSU | p value | ||
|---|---|---|---|
| Positive ANA (n = 100) | Negative ANA (n = 223) | ||
| Total eosinophil (cell/microL), median (min-max) | 113 (13-399) | 148 (11-746) | 0.177 |
| Eosinophilia (≥500 eosinophils/microL), n (%) | 3/71 (4.2%) | 9/148 (6.1%) | 0.755 |
| Total white blood cell (cell/microL), median (min-max) | 6,380 (2,053-13,100) | 6,385 (2,048-17,220) | 0.748 |
| Leukopenia (<4,000 white blood cell/microL), n (%) | 22/94 (23.4%) | 58/206 (28.2%) | 0.388 |
| Erythrocyte sedimentation rate (ESR) (mm/hr) (normal ≤ 20 mm/hr), median (min-max) | 18 (4-84) | 14 (1-60) | 0.007∗ |
| Stool exam: Blastocystis hominis, n (%) | 1/42 (2.4%) | 4/85 (4.7%) | 1.00 |
| HBsAg (positive), n (%) | 1/57 (1.8%) | 5/127 (3.9%) | 0.668 |
| Anti HCV (positive), n (%) | 2/52 (3.8%) | 0/104 (0.0%) | 0.110 |
| Thyroid microsomal antibody (positive), n (%) | 1/15 (6.7%) | 3/30 (10.0%) | 1.000 |
| Antithyroid peroxidase (anti-TPO) (positive), n (%) | 8/40 (20.0%) | 11/75 (14.7%) | 0.463 |
| Antithyroglobulin antibody (positive), n (%) | 15/52 (28.8%) | 22/109 (20.2%) | 0.222 |
| T3, n (%) | 0.713 | ||
| Low | 2/19 (10.5%) | 7/45 (15.6%) | |
| FT4, n (%) | 0.614 | ||
| Low | 3/24 (12.5%) | 2/42 (4.8%) | |
| High | 1/24 (4.2%) | 2/42 (4.8%) | |
| TSH, n (%) | 0.834 | ||
| Low | 1/58 (1.7%) | 5/122 (4.1%) | |
| High | 3/58 (5.2%) | 7/122 (5.7%) | |
| D-dimer (>500 ng/mL), n (%) | 7/14 (50.0%) | 14/37 (37.8%) | 0.431 |
| IgE (>100 IU/mL), n (%) | 13/18 (72.2%) | 22/38 (57.9%) | 0.301 |
| Autologous serum skin test (positive), n (%) | 4/18 (22.2%) | 14/39 (35.9%) | 0.302 |
| Skin prick pest (positive), n (%) | 6/15 (40.0%) | 26/45 (57.8%) | 0.232 |
∗ indicated statistical significance.