Table 3.
Release kinetics of MLX and DEX from transfersomes.
| Formulation codes | Zero order | First order | Higuchi model | Korsmeyer-Peppas model | ||||
|---|---|---|---|---|---|---|---|---|
| R 2 | K 0 | R 2 | K 1 | R 2 | K H | R 2 | n | |
| TFS-1 (MLX) | 0.8605 | 7.287 | 0.9911 | 0.124 | 0.9777 | 21.095 | 0.9914 | 0.604 |
| TFS-2 (MLX) | 0.7884 | 7.563 | 0.9667 | 0.135 | 0.9875 | 22.079 | 0.9896 | 0.538 |
| TFS-3 (MLX) | 0.7899 | 8.362 | 0.9868 | 0.164 | 0.9811 | 24.401 | 0.9841 | 0.546 |
| TFS-4 (MLX) | 0.8920 | 6.895 | 0.9732 | 0.111 | 0.9319 | 19.774 | 0.9654 | 0.678 |
| TFS-5 (MLX) | 0.7193 | 7.617 | 0.9245 | 0.138 | 0.9892 | 22.356 | 0.9895 | 0.485 |
| TFS-6 (MLX) | 0.7399 | 7.644 | 0.9367 | 0.139 | 0.9938 | 22.404 | 0.9938 | 0.496 |
| TFS-1 (DEX) | 0.8605 | 7.287 | 0.9922 | 0.146 | 0.9763 | 23.124 | 0.9894 | 0.602 |
| TFS-2 (DEX) | 0.7884 | 7.563 | 0.9601 | 0.155 | 0.9845 | 23.538 | 0.9847 | 0.491 |
| TFS-3 (DEX) | 0.7899 | 8.362 | 0.9723 | 0.182 | 0.9909 | 25.411 | 0.9925 | 0.469 |
| TFS-4 (DEX) | 0.8920 | 6.895 | 0.9096 | 0.131 | 0.9934 | 21.684 | 0.9963 | 0.459 |
| TFS-5 (DEX) | 0.7193 | 7.617 | 0.9390 | 0.151 | 0.9902 | 23.433 | 0.9903 | 0.490 |
| TFS-6 (DEX) | 0.7399 | 7.644 | 0.9488 | 0.142 | 0.9991 | 22.601 | 0.9994 | 0.487 |