| Study ID | Study follow‐up (months) | NVX‐CoV2373 (n) | Placebo (n) | Critical outcomes | ||||||
| Confirmed SARS‐CoV‐2 infection after complete vaccination | Confirmed symptomatic COVID‐19 after complete vaccination | Severe or critical COVID‐19 | All‐cause mortality | Systemic reactogenicity events | Any AE | SAE | ||||
| Keech 2020 (NCT04368988) | 1.15 | 29 | 25 | * | * | * | * | * | ✓ | ✓ |
| Dunkle 2021 (NCT04611802) | 2 | 19,965 | 9984 | * | ✓ | ✓ | ✓ | ✓ | ✓ | ✓ |
| Formica 2021 (NCT04368988) | 1.15 | 258 | 257 | * | * | * | * | ✓ | ✓ | ✓ |
| Heath 2021 (NCT04583995; EudraCT 2020‐004123‐16) | 13 | 7593 | 7594 | * | ✓ | ✓ | ✓ | * | ✓ | ✓ |
| Shinde 2021 (NCT04533399; PACTR202009726132275) | 1.15 | 2206 | 2200 | * | ✓ | ✓ | * | ✓ | ✓ | ✓ |
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