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. 2022 Dec 7;2022(12):CD015477. doi: 10.1002/14651858.CD015477
Outcome  No. of studies No. of participants Statistical method Effect size Vaccine efficacy (95% CI)
Confirmed SARS‐CoV‐2 infection after complete vaccination N/A  N/A  N/A  N/A  N/A 
Confirmed symptomatic COVID‐19 after complete vaccination 1 18,695 N/A  N/A  91.10% (83.80% to 95.10%)
Severe or critical COVID‐19 after complete vaccination 1 19,866 N/A  N/A  100.00% (94.40% to 100.00%)
All‐cause mortality  1 21,862 Risk Ratio (M‐H, Random, 95% CI) 0.99 (0.10 to 9.54) N/A 
Serious adverse events 1 21,862 Risk Ratio (M‐H, Random, 95% CI) 0.65 (0.39 to 1.07) N/A 
Systemic reactogenicity events N/A  N/A  N/A  N/A  N/A 
Any adverse event N/A  N/A  N/A  N/A  N/A 
Local reactogenicity events  N/A  N/A  N/A  N/A  N/A