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. 2022 Dec 7;2022(12):CD015477. doi: 10.1002/14651858.CD015477
Outcome  No. of studies No. of participants Statistical method Effect size Vaccine efficacy (95% CI)
Confirmed SARS‐CoV‐2 infection after complete vaccination N/A N/A N/A N/A N/A
Confirmed symptomatic COVID‐19 after complete vaccination N/A N/A N/A N/A N/A
Severe or critical COVID‐19 after complete vaccination N/A N/A N/A N/A N/A
All‐cause mortality  1 28,254 Risk Ratio (M‐H, Random, 95% CI) 1.27 (0.52 to 3.05) N/A
Serious adverse events N/A N/A N/A N/A N/A
Systemic reactogenicity events 1 119 Risk Ratio (M‐H, Random, 95% CI) 1.80 (0.71 to 4.56) N/A
Any adverse event N/A N/A N/A N/A N/A
Local reactogenicity events  1 119 Risk Ratio (M‐H, Random, 95% CI) 6.46 (3.18 to 13.13) N/A