Table 2.
HLA class I typing of donors and ESRD patients.
| Related donor | Unrelated donor | |||||
|---|---|---|---|---|---|---|
| Donor (N = 252)* | Recipient (N = 252)* | P value | Donor (N = 216)* | Recipient (N = 196)* | P value | |
| HLA-A | ||||||
| 1 | 7 (2.8) | 4 (1.6) | .367 | 3 (1.4) | 4 (2.0) | .611 |
| 2 | 64 (25.4) | 68 (27.0) | .685 | 42 (19.4) | 43 (21.9) | .532 |
| 3 | 2 (0.8) | 1 (0.4) | .570 | 4 (1.9) | 1 (0.5) | .246 |
| 11 | 74 (29.4) | 82 (32.5) | .441 | 65 (30.1) | 62 (31.6) | .735 |
| 23 | 1 (0.4) | 0 (0.0) | – | |||
| 24 | 39 (15.5) | 44 (17.5) | .548 | 45 (20.8) | 31 (15.8) | .191 |
| 26 | 3 (1.2) | 4 (1.6) | .704 | 7 (3.2) | 5 (2.6) | .678 |
| 29 | 24 (9.5) | 22 (8.7) | .757 | 12 (5.6) | 19 (9.7) | .116 |
| 30 | 5 (2.0) | 3 (1.2) | .481 | 2 (0.9) | 6 (3.1) | .139 |
| 31 | 1 (0.4) | 2 (0.8) | .570 | 2 (0.9) | 4 (2.0) | .358 |
| 32 | 1 (0.4) | 0 (0.0) | – | 1 (0.5) | 0 (0.0) | – |
| 33 | 25 (9.9) | 17 (6.7) | .200 | 29 (13.4) | 19 (9.7) | .240 |
| 34 | 2 (0.8) | 4 (1.6) | .421 | 3 (1.4) | 0 (0.0) | – |
| 68 | 1 (0.4) | 1 (0.4) | 1.000 | 1 (0.5) | 0 (0.0) | – |
| 74 | 3 (1.2) | 0 (0.0) | – | 0 (0.0) | 1 (0.5) | – |
| 36 | 0 (0.0) | 1 (0.5) | – | |||
| HLA-B | ||||||
| 7 | 30 (11.9) | 28 (11.1) | .780 | 17 (7.9) | 28 (14.3) | .040 |
| 13 | 12 (4.8) | 13 (5.2) | .837 | 13 (6.0) | 8 (4.1) | .375 |
| 14 | 1 (0.4) | 0 (0.0) | – | 1 (0.5) | 0 (0.0) | – |
| 15 | 62 (24.6) | 66 (26.2) | .682 | 48 (22.2) | 51 (26.0) | .368 |
| 18 | 6 (2.4) | 4 (1.6) | .526 | 4 (1.9) | 2 (1.0) | .488 |
| 27 | 6 (2.4) | 9 (3.6) | .435 | 12 (5.6) | 2 (1.0) | .024 |
| 35 | 14 (5.6) | 14 (5.6) | 1.000 | 9 (4.2) | 2 (1.0) | .068 |
| 37 | 2 (0.8) | 2 (0.8) | 1.000 | 4 (1.9) | 0 (0.0) | – |
| 38 | 17 (6.7) | 14 (5.6) | .579 | 10 (4.6) | 16 (8.2) | .146 |
| 39 | 7 (2.8) | 6 (2.4) | .779 | 3 (1.4) | 3 (1.5) | .905 |
| 40 | 12 (4.8) | 16 (6.3) | .438 | 20 (9.3) | 17 (8.7) | .835 |
| 41 | 1 (0.4) | 0 (0.0) | – | – | ||
| 44 | 2 (0.8) | 3 (1.2) | .655 | 6 (2.8) | 1 (0.5) | .113 |
| 46 | 18 (7.1) | 20 (7.9) | .736 | 18 (8.3) | 22 (11.2) | .324 |
| 48 | 5 (2.0) | 5 (2.0) | 1.000 | 2 (0.9) | 3 (1.5) | .580 |
| 51 | 10 (4.0) | 8 (3.2) | .632 | 8 (3.7) | 10 (5.1) | .490 |
| 52 | 1 (0.4) | 4 (1.6) | .213 | 4 (1.9) | 2 (1.0) | .488 |
| 53 | 1 (0.4) | 1 (0.4) | 1.000 | |||
| 54 | 5 (2.0) | 10 (4.0) | .199 | 8 (3.7) | 6 (3.1) | .720 |
| 55 | 5 (2.0) | 4 (1.6) | .737 | 3 (1.4) | 5 (2.6) | .400 |
| 56 | 9 (3.6) | 4 (1.6) | .171 | 5 (2.3) | 3 (1.5) | .567 |
| 57 | 9 (3.6) | 6 (2.4) | .435 | 3 (1.4) | 5 (2.6) | .400 |
| 58 | 17 (6.7) | 14 (5.6) | .579 | 18 (8.3) | 9 (4.6) | .131 |
| 67 | 0 (0.0) | 1 (0.4) | – | – | ||
| 45 | – | 0 (0.0) | 1 (0.5) | – | ||
Bold values indicate statistical significance.
ESRD = end-stage renal disease, HLA = human leukocyte antigen.
*
Number of alleles.