Skip to main content
. 2022 Dec 2;101(48):e31856. doi: 10.1097/MD.0000000000031856

Table 3.

HLA class II typing of donors and ESRD patients.

Related donor Unrelated donor
Donor (N = 252)* Recipient (N = 252)* P value Donor (N = 216)* Recipient (N = 196)* P value
HLA-DRB1
 1 1 (0.4) 1 (0.4) 1.000 1 (0.5) 0 (0.0)
 3 12 (4.8) 9 (3.6) .505 14 (6.5) 6 (3.1) .115
 4 27 (10.7) 32 (12.7) .489 18 (8.3) 22 (11.2) .324
 7 13 (5.2) 8 (3.2) .270 14 (6.5) 8 (4.1) .283
 8 8 (3.2) 9 (3.6) .805 7 (3.2) 9 (4.6) .481
 9 30 (11.9) 31 (12.3) .891 26 (12.0) 19 (9.7) .447
 10 22 (8.7) 25 (9.9) .646 14 (6.5) 15 (7.7) .643
 11 5 (2.0) 10 (4.0) .199 3 (1.4) 8 (4.1) .106
 12 73 (29.0) 84 (33.3) .290 59 (27.3) 69 (35.2) .085
 13 11 (4.4) 6 (2.4) .224 12 (5.6) 4 (2.0) .077
 14 13 (5.2) 9 (3.6) .386 16 (7.4) 13 (6.6) .759
 15 33 (13.1) 25 (9.9) .265 24 (11.1) 19 (9.7) .639
 16 4 (1.6) 3 (1.2) .704 8 (3.7) 3 (1.5) .186
 18 0 (0.0) 1 (0.5)
HLA-DQA1
 1 86 (34.1) 80 (31.7) .570 82 (38.0) 64 (32.7) .261
 2 13 (5.2) 8 (3.2) .270 14 (6.5) 7 (3.6) .186
 3 56 (22.2) 60 (23.8) .672 41 (19.0) 40 (20.4) .716
 4 12 (4.8) 19 (7.5) .198 8 (3.7) 8 (4.1) .843
 5 25 (9.9) 22 (8.7) .646 25 (11.6) 17 (8.7) .333
 6 60 (23.8) 63 (25.0) .756 46 (21.3) 60 (30.6) .031
HLA-DQB1
 1 0 (0.0) 3 (1.2) 1 (0.5) 0 (0.0)
 2 16 (6.3) 15 (6.0) .853 27 (12.5) 9 (4.6) .006
 3 135 (53.6) 145 (57.5) .370 100 (46.3) 111 (56.6) .036
 4 15 (6.0) 17 (6.7) .715 9 (4.2) 12 (6.1) .370
 5 67 (26.6) 58 (23.0) .354 62 (28.7) 43 (21.9) .116
 6 19 (7.5) 14 (5.6) .370 17 (7.9) 21 (10.7) .321

Bold values indicate statistical significance.

ESRD = end-stage renal disease, HLA = human leukocyte antigen.

*

Number of alleles.