Table 3.
HLA class II typing of donors and ESRD patients.
Related donor | Unrelated donor | |||||
---|---|---|---|---|---|---|
Donor (N = 252)* | Recipient (N = 252)* | P value | Donor (N = 216)* | Recipient (N = 196)* | P value | |
HLA-DRB1 | ||||||
1 | 1 (0.4) | 1 (0.4) | 1.000 | 1 (0.5) | 0 (0.0) | – |
3 | 12 (4.8) | 9 (3.6) | .505 | 14 (6.5) | 6 (3.1) | .115 |
4 | 27 (10.7) | 32 (12.7) | .489 | 18 (8.3) | 22 (11.2) | .324 |
7 | 13 (5.2) | 8 (3.2) | .270 | 14 (6.5) | 8 (4.1) | .283 |
8 | 8 (3.2) | 9 (3.6) | .805 | 7 (3.2) | 9 (4.6) | .481 |
9 | 30 (11.9) | 31 (12.3) | .891 | 26 (12.0) | 19 (9.7) | .447 |
10 | 22 (8.7) | 25 (9.9) | .646 | 14 (6.5) | 15 (7.7) | .643 |
11 | 5 (2.0) | 10 (4.0) | .199 | 3 (1.4) | 8 (4.1) | .106 |
12 | 73 (29.0) | 84 (33.3) | .290 | 59 (27.3) | 69 (35.2) | .085 |
13 | 11 (4.4) | 6 (2.4) | .224 | 12 (5.6) | 4 (2.0) | .077 |
14 | 13 (5.2) | 9 (3.6) | .386 | 16 (7.4) | 13 (6.6) | .759 |
15 | 33 (13.1) | 25 (9.9) | .265 | 24 (11.1) | 19 (9.7) | .639 |
16 | 4 (1.6) | 3 (1.2) | .704 | 8 (3.7) | 3 (1.5) | .186 |
18 | 0 (0.0) | 1 (0.5) | – | |||
HLA-DQA1 | ||||||
1 | 86 (34.1) | 80 (31.7) | .570 | 82 (38.0) | 64 (32.7) | .261 |
2 | 13 (5.2) | 8 (3.2) | .270 | 14 (6.5) | 7 (3.6) | .186 |
3 | 56 (22.2) | 60 (23.8) | .672 | 41 (19.0) | 40 (20.4) | .716 |
4 | 12 (4.8) | 19 (7.5) | .198 | 8 (3.7) | 8 (4.1) | .843 |
5 | 25 (9.9) | 22 (8.7) | .646 | 25 (11.6) | 17 (8.7) | .333 |
6 | 60 (23.8) | 63 (25.0) | .756 | 46 (21.3) | 60 (30.6) | .031 |
HLA-DQB1 | ||||||
1 | 0 (0.0) | 3 (1.2) | – | 1 (0.5) | 0 (0.0) | – |
2 | 16 (6.3) | 15 (6.0) | .853 | 27 (12.5) | 9 (4.6) | .006 |
3 | 135 (53.6) | 145 (57.5) | .370 | 100 (46.3) | 111 (56.6) | .036 |
4 | 15 (6.0) | 17 (6.7) | .715 | 9 (4.2) | 12 (6.1) | .370 |
5 | 67 (26.6) | 58 (23.0) | .354 | 62 (28.7) | 43 (21.9) | .116 |
6 | 19 (7.5) | 14 (5.6) | .370 | 17 (7.9) | 21 (10.7) | .321 |
Bold values indicate statistical significance.
ESRD = end-stage renal disease, HLA = human leukocyte antigen.
Number of alleles.