Figure 3.

Shared ancestry of alleles between the S. eubayanus component of S. pastorianus genomes (CBS 1538 and W34/70) and Holarctic clade S. eubayanus isolates. Coloured offset vertical lines represent sites where an allele in a S. pastorianus strain is also present in only one other population (Tibet = Blue, Ireland = Magenta, or North Carolina = Green) in the Holarctic clade. Coloured rectangles represent blocks assigned to these populations, where blocks contain two or more neighboring alleles from the same population (borders are drawn at half the distance between the outermost sites). All alleles were called by alignment to the UCD646 assembly. Sites where a genotype could not be called or were filtered out are shown in black. All chromosome comparisons are shown in Figure S2 (Supporting Information), and supporting data is in Table S1 (Supporting Information). (A) Shared ancestry blocks of CBS 1538 and W34/70 on Chr XVI. CBS 1538 and W34/70 have similar patterns of ancestry except for a large region marked with a red box where CBS 1538 has shared ancestry with the Tibet population and W34/70 has shared ancestry with the Irish population. In addition, there are large regions in W34/70 where shared ancestry could not be reliably assigned. (B) Shared ancestry blocks of CBS 1538 and W34/70 on Chr XII. This example shows shared ancestry with all three Holarctic populations, although blocks assigned to North Carolina are shorter and fewer in number compared to Irish or Tibet blocks. Again, W34/70 has large blocks where no shared ancestry could be assigned.