Table 3.
Hospital-Adjusted Logistic Regression Showing Antibiotics Use in the pre- intra- and post- operative periods
| Parameter | Preoperative Period | Intraoperative Period | Postoperative Period | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Antibiotics Administered No (%) Yes (%) |
aOR (95% CI) |
P
Value |
Antibiotics Administered No (%) Yes (%) |
aOR (95% CI) |
P
Value |
Antibiotics Administered No (%) Yes (%) |
aOR (95% CI) |
P
Value |
||||
| Sex | ||||||||||||
| Female | 112 (42.6) |
327 (66.7) |
1 | 316 (62.7) |
122 (49.2) |
22 (36.7) |
416 (60.1) |
|||||
| Male | 151 (57.4) |
163 (33.3) |
0.9 (0.6–1.6) |
.889 | 188 (37.3) |
126 (50.8) |
0.9 (0.6–1.5) |
.792 | 38 (63.3) |
276 (39.9) |
1.3 (0.7–2.5) |
.327 |
| Age group | ||||||||||||
| <25 y | 52 (19.8) |
159 (32.5) |
1 | 157 (31.1) |
54 (21.8) |
8 (13.3) |
203 (29.3) |
|||||
| 25–44 y | 127 (48.3) |
265 (54.1) |
1.2 (0.7–2.1) |
.457 | 258 (51.2) |
133 (53.6) |
1.1 (0.6–2.1) |
.781 | 30 (50) |
362 (52.3) |
0.8 (0.3–1.9) |
.611 |
| 45–64 y | 66 (25.1) |
47 (9.6) |
0.6 (0.3–1.3) |
.212 | 66 (13.1) |
47 (18.9) |
0.8 (0.4–1.7) |
.551 | 19 (31.7) |
93 (13.4) |
0.6 (0.2–1.6) |
.317 |
| ≥65 y | 18 (6.8) |
19 (3.9) |
0.9 (0.3–2.7) |
.847 | 23 (4.6) |
14 (5.7) |
1.0 (0.4–2.6) |
.987 | 3 (5.0) |
34 (4.9) |
1.5 (0.3–6.3) |
.582 |
| Alcohol | ||||||||||||
| No | 227 (86.6) |
449 (91.6) |
1 | 455 (90.3) |
220 (89.1) |
51 (85) |
624 (90.3) |
|||||
| Yes | 35 (13.4) |
41 (8.4) |
0.8 (0.4–1.7) |
.519 | 49 (9.7) |
27 (10.9) |
0.7 (0.4–1.4) |
.340 | 9 (15) |
67 (9.7) |
1.0 (0.4–2.2) |
.948 |
| Presence of comorbidity | ||||||||||||
| No | 200 (76.0) |
435 (88.8) |
1 | 452 (89.7) |
182 (73.4) |
46 (76.7) |
588 (85.0) |
|||||
| Yes | 63 (24.0) |
55 (11.2) |
1.3 (0.7–2.1) |
.411 | 52 (10.3) |
66 (26.6) |
1.2 (0.7–2.1) |
.483 | 14 (23.3) |
104 (15.0) |
1.1 (0.6–2.2) |
.741 |
| Type of surgery | ||||||||||||
| Nonabdominal | 43 (16.4) |
13 (2.6) |
1 | 28 (5.6) |
28 (11.3) |
30 (33.3) |
35 (5.1) |
|||||
| Intra-abdominal | 171 (65.0) |
217 (44.3) |
2.7 (1.1–6.7) |
.034 | 231 (45.8) |
156 (62.9) |
1.2 (0.6–2.2) |
.639 | 39 (65.0) |
349 (50.4) |
3.6 (1.9–7.2) |
<.001 |
| Obstetric | 49 (18.6) |
260 (53.1) |
1.5 (0.5–4.7) |
.483 | 245 (48.6) |
64 (25.8) |
0.6 (0.1–2.8) |
.489 | 1 (1.7) |
308 (44.5) |
11.8 (0.7–205.5) |
.089 |
| Wound class | ||||||||||||
| Clean | 165 (62.7) |
419 (85.5) |
1 | 439 (87.1) |
144 (58.1) |
42 (70) |
541 (78.2) |
|||||
| Clean-contaminated | 89 (33.8) |
49 (10.0) |
6.3 (2.3–16.8) |
<.001 | 60 (11.9) |
78 (31.4) |
2.9 (1.7–5.0) |
<.001 | 18 (30) |
120 (17.3) |
3.1 (1.6–5.9) |
<.001 |
| Contaminated | 9 (3.4) |
22 (4.5) |
47.4 (14.5–155.4) |
<.001 | 5 (1.0) |
26 (10.5) |
7.1 (2.5–20.0) |
<.001 | 0 (0) |
31 (4.5) |
34.9 (2.1–587.8) |
.014 |
| Consistency of indication to guidelines | ||||||||||||
| No | 174 (66.2) |
169 (34.5) |
1 | … | 228 (45.2) |
114 (46.0) |
53 (88.3) |
289 (41.8) |
||||
| Yes | 89 (33.8) |
321 (65.5) |
3.4 (2.1–5.7) |
<.001 | 276 (54.8) |
134 (54.0) |
3.4 (1.9–5.9) |
<.001 | 7 (11.7) |
403 (58.2) |
4.3 (1.8–10.1) |
.001 |
Note. OR, odds ratio; CI, confidence interval.