Table 1.
Demographic and clinical characteristics of cases hospitalized in the six participating PHO units.
| Unit 1 | Unit 2 | Unit 3 (BMT) | Unit 4 | Unit 5 | Unit 6 | TOTAL | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| N | % | N | % | N | % | N | % | N | % | N | % | N | % | |
| Gender | ||||||||||||||
| Male | 159 | 44.8 | 240 | 54.2 | 151 | 57.4 | 68 | 58.6 | 261 | 60.1 | 120 | 53.1 | 999 | 54.4 |
| Female | 196 | 55.2 | 203 | 45.8 | 112 | 42.6 | 48 | 41.4 | 173 | 39.9 | 106 | 46.9 | 838 | 45.6 |
| Median | IQR | Median | IQR | Median | IQR | Median | IQR | Median | IQR | Median | IQR | Median | IQR | |
| Age (years) | 5.2 | 2.7-8.7 | 6.4 | 3.2-11.6 | 8.1 | 4-13.2 | 6.7 | 4.4-12.7 | 8.4 | 3.8-12.6 | 5.5 | 3.4-7.8 | 6.5 | 3.5-11.7 |
| Underlying disease | ||||||||||||||
| Solid tumors | 194 | 54.7 | 203 | 45.8 | 38 | 14.5 | 56 | 48.3 | 185 | 42.5 | 43 | 19.0 | 719 | 39.1 |
| Hematologic malignancies | 188 | 44.5 | 250 | 49.0 | 154 | 55.9 | 67 | 50.9 | 258 | 54.5 | 188 | 79.2 | 1105 | 54.2 |
| Other* | 3 | 0.9 | 23 | 5.2 | 78 | 29.7 | 1 | 0.9 | 13 | 3.0 | 4 | 1.8 | 122 | 6.6 |
| Pediatric Hospitals | General Hospitals | |||||||||||||
| N | % | N | % | p value | ||||||||||
| Gender | 0.001 | |||||||||||||
| Male | 720 | 57.3% | 279 | 48% | ||||||||||
| Female | 536 | 42.7% | 302 | 52% | ||||||||||
| Underlying disease | 0.001 | |||||||||||||
| Solid tumors | 482 | 38.4% | 237 | 40.8% | ||||||||||
| Hematologic malignancies | 729 | 52.5% | 376 | 58% | ||||||||||
| Other* | 115 | 9.2% | 7 | 1.2% | ||||||||||
*Other: Aplastic anemia, Fanconi anemia, β-thalassemia, immunodeficiencies (Wiskott Aldrich syndrome, chronic granulomatous disease, severe congenital neutropenia), Langerhans cell histiocytosis, Hemophagocytic lymphohistiocytosis, osteopetrosis, mitochondrial neurogastrointestinal encephalomyopathy.