Table 2.
Use of antibiotics before (PRE) and after (POST) PHIG intervention. Unit 4 did not participate in data collection after intervention.
Unit 1 | Unit 2 | Unit 3 (BMT) | Unit 4 | Unit 5 | Unit 6 | TOTAL | Pediatric hospitals | General hospitals | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | Pre | Post | |
Patients | 169 | 186 | 187 | 256 | 103 | 160 | 116 | 173 | 262 | 100 | 126 | 848 | 990 | 579 | 678 | 269 | 312 | |
Antibiotic days | 2030 | 2446 | 4135 | 6238 | 4349 | 5181 | 7539 | 1093 | 1291 | 1528 | 2201 | 20674 | 17358 | 17116 | 12710 | 3558 | 4647 | |
Patient days | 4253 | 5775 | 6832 | 11929 | 4450 | 5310 | 18019 | 2920 | 5407 | 3485 | 6255 | 39959 | 34677 | 32221 | 22646 | 7738 | 12030 | |
LOT/ 1,000 patient days | 477 | 424 | 605 | 523 | 977 | 976 | 418 | 374 | 239 | 438 | 352 | 517 | 501 | 531 | 561 | 460 | 386 | |
DOT/LOT ratio | 2.6 | 2.8 | 2.1 | 1.7 | 1.5 | 1.5 | 1.6 | 2.1 | 2.2 | 2.2 | 1.3 | 2.0 | 2.0 | 1.9 | 1.9 | 2.4 | 2.2 | |
Most commonly used antibiotics - % of DOTS as recorded during first 7 days of treatment | ||||||||||||||||||
Amik/Genta | 27.7 | 28.1 | 14.6 | 9.6 | 6.5 | 3.5 | 22.6 | 26.4 | 28.8 | 24.4 | 19.4 | 21.7 | 20.2 | 18.6 | 16.6 | 26.6 | 25.9 | |
Cefepime | 0.1 | 0.0 | 0.5 | 0.6 | 0.4 | 0.4 | 0.0 | 25.5 | 20.9 | 6.9 | 6.4 | 6.1 | 6.5 | 8.4 | 9.5 | 2.4 | 1.6 | |
Ceftr/Cefotax | 7.6 | 3.6 | 3.0 | 8.9 | 2.5 | 1.0 | 9.8 | 2.8 | 1.4 | 3.3 | 6.4 | 5.0 | 4.0 | 4.2 | 3.8 | 6.2 | 4.3 | |
Ceftazidime | 18.9 | 0.0 | 0.0 | 0.0 | 0.6 | 1.5 | 0.4 | 0.0 | 0.0 | 19.0 | 4.5 | 7.3 | 0.6 | 0.2 | 0.4 | 19.0 | 1.1 | |
Cipro/Levo | 1.3 | 1.5 | 0.6 | 0.5 | 1.5 | 10.1 | 0 | 1.8 | 0.5 | 0.9 | 0.6 | 1.1 | 2.1 | 1.0 | 2.7 | 1.2 | 1.3 | |
Colistin | 0.7 | 2.3 | 0.3 | 0.0 | 1.5 | 0.5 | 0.4 | 0.0 | 0.0 | 0.2 | 0.5 | 0.4 | 0.8 | 0.4 | 0.1 | 0.5 | 1.8 | |
Meropenem | 4.7 | 4.5 | 5.4 | 4.4 | 6.4 | 7.9 | 1.3 | 4.0 | 3.9 | 7.8 | 13.8 | 4.8 | 5.7 | 4.3 | 5.0 | 5.7 | 6.8 | |
Metronidazole | 4.2 | 4.2 | 4.1 | 1.3 | 1.2 | 4.7 | 2.3 | 1.5 | 1.2 | 3.2 | 8.4 | 3 | 3.3 | 2.4 | 2.1 | 3.9 | 5.3 | |
Pip/Tazo | 0.7 | 24.2 | 33.3 | 39.8 | 52.4 | 39.7 | 46.6 | 9.3 | 15.4 | 2.4 | 37.1 | 20 | 28.4 | 31.5 | 29.1 | 1.3 | 27.4 | |
Vanc/Teico | 32.8 | 30 | 35.9 | 30.8 | 23.2 | 25.6 | 10.9 | 23.9 | 25.3 | 25.9 | 31.7 | 27 | 28.4 | 24.9 | 30.4% | 27.2 | 30.4 |
Amik/Genta=Amikacin/Gentamycin; Ceft/Cefotax=Ceftriaxone/Cefotaxime; Cipro/Levo= Ciprofloxacin/ Levofloxacin; Pip/Tazo= Piperacillin/Tazobactam Vanc/Teico=Vancomycin/Teicoplanin.