Table III.
Correlation between drug concentration and lysis time
| Drug Concentration | DOAC | Lysis time | Δ Concentration | Δ Lysis time | ||
|
|
|
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| Dabigatran (n=62) | rho | −0.251 | rho | −0.525 | ||
| p | 0.053 | p | 0.003 | |||
|
|
|
|||||
| Apixaban (n=76) | rho | −0.032 | rho | −0.061 | ||
| p | 0.79 | p | 0.72 | |||
|
|
|
|||||
| Edoxaban (n=58) | rho | −0.153 | rho | −0.054 | ||
| p | 0.25 | p | 0.78 | |||
|
|
|
|||||
| Rivaroxaban (n=78) | rho | −0.180 | rho | −0.212 | ||
| p | 0.115 | p | 0.196 | |||
Correlations (rho) were calculated between drug concentration and lysis time by combining C-Trough and C-Peak samples (left), and between peak-trough differences (Δ) in drug concentration and lysis time (right), in which case the number of pairs is halved. DOAC: direct oral anticoagulant.