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. 2022 Aug 18;30(1):278–284. doi: 10.1245/s10434-022-12399-y

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Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — mVAF comparison by primary tumor site in stage IV disease. ctDNA levels were compared in patients with stage IV disease (n = 212) based on primary tumor site. Stage IV colorectal cancer had the highest level of ctDNA, followed by upper GI and HPB (41.1 ± 63.8, 24.1 ± 41.6, and 9.91 ± 23.9, respectively; p < 0.05). mVAF maximum variant allele frequency, ctDNA circulating tumor DNA, GI gastrointestinal, HPB hepato-pancreato-biliary