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. 2022 Nov 23;13:1025483. doi: 10.3389/fpsyt.2022.1025483

TABLE 5.

Mean (SD) understanding of each level of hypothetical polygenic risk score for alcohol use disorder.

Condition Below-average PRS
Average PRS
Above-average PRS
F-test
M (SD) M (SD) M (SD)
Control 2.48 (1.04) 2.16 (1.20) 2.23 (1.02) F (1.9,201.4)
= 5.09; p < 0.01
AUD Edu 2.45 (0.93) 2.27 (0.99) 2.41 (0.80) F (2,206) = 2.55; p = 0.08
PRS + AUD
Edu
2.82 (0.96) 2.78 (0.99) 2.67 (0.95) F (2,220) = 2.22; p = 0.11

Four items were included to assess understanding of each PRS. Items were scored as correct or incorrect and summed to create a sum score for each scenario. Range = 0–4. PRS, polygenic risk score.