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In vivo effects of Type B trichothecenes like DON and microbial detoxification approaches. (A) DON affects the gastrointestinal system and at a molecular level, the mycotoxin can bind to ribosomes triggering ribotoxic stress. (B–F) DON can be transformed by de-epoxidation, oxidation, epimerization, acetylation, hydroxylation and glycosylation.
