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CD4 T cell responses. Multifunctional analyses week 22. Cytokine production by CD4+ T cells assayed by ICS. Multifunctional responses after stimulation with pools of overlapping peptides from MOMP are represented. The size of each pie is proportional to the percentage of CD154+CD4+ T cells expressing at least one cytokine, including IFN-γ, TNF-α, and IL-2, and the proportions of cells expressing IFN-γ and/or TNF-α and/or IL-2 cytokines are displayed in each pie.
