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. 2022 Oct 10;127(12):2141–2153. doi: 10.1038/s41416-022-02006-y

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© The Author(s), under exclusive licence to Springer Nature Limited 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 3 — a General polysome profiles in FGF14-AS2-overexpressing and FGF14-AS2-knockdown MDA-MB-231 cells. Polyribosomes within the box indicated by the dotted line represent active translation. b Percentage of RUNX2 mRNA in each fraction in FGF14-AS2-overexpressing and FGF14-AS2-knockdown MDA-MB-231 cells. Fractions #1–7 represent non-translated mRNA, whereas fractions #8–13 represent actively translated mRNA. c Ratios of actively translated RUNX2 mRNA to non-translated RUNX2 mRNA in FGF14-AS2-overexpressing and FGF14-AS2-knockdown MDA-MB-231 cells. Fractions #1–7 (representing non-translated RUNX2 mRNA group) were pooled, as were fractions #8–13 (representing translated RUNX2 mRNA group). The data are shown as the mean ± s.d. of at least three independent experiments. **P < 0.005, ***P < 0.001.