Table 4.
Comparisons of the Levels of Anti-RBD-Specific IgA and IgG in Participants’ Milk Following the Vaccine Booster (N = 12).
| Time (Day) | IgA Analysis |
IgG Analysis |
Group Comparison |
||||
|---|---|---|---|---|---|---|---|
| Mdn | UL, LL | p | Mdn | UL, LL | p | p | |
| -30 | -0.954 | 36.28, -10.08 | 0.9926 | 6.281 | 12.85, 4.16 | >0.9999 | 0.0394 |
| -1 | -2.433 | 20.74, -10.32 | - | 5.548 | 9.46, 2.68 | - | 0.0004 |
| 7 | 9.069 | 55.74, -1.32 | <0.0001 | 9.058 | 143.02, 4.56 | 0.0380 | >0.9999 |
| 14 | -1.600 | 49.36, -7.00 | 0.9659 | 22.945 | 294.35, 3.15 | <0.0001 | <0.0001 |
| 21 | -1.117 | 41.03, -11.02 | 0.3060 | 15.461 | 294.35, 3.93 | <0.0001 | <0.0001 |
| 30 | -1.471 | 18.48, -8.80 | 0.7981 | 14.419 | 235.67, 3.83 | <0.0001 | <0.0001 |
| 45 | 0.795 | 26.91, -7.60 | 0.0479 | 12.801 | 296.85, 3.07 | 0.0003 | <0.0001 |
| 60 | 7.915 | 32.81, -7.44 | <0.0001 | 28.243 | 294.35, 3.31 | <0.0001 | 0.0252 |
Note. Median IgA and IgG levels are reported in units/ml (U/ml). Negative values indicate that the standardized sample value was lower than the negative control milk value. The p values reported within each IgA and IgG analysis column were determined via a Dunn’s multiple comparisons test where the dataset from each time was compared to the dataset from Day -1. The p values reported in the last column are from a Dunn’s multiple comparisons test evaluating differences between IgA and IgG levels at each time point. Missing values: Day -30 = 4, Day -1 = 2, Day 7 = 5 for the IgA analysis and 3 for the IgG analysis, Day 14 = 2, Day 21 = 3, Day 30 = 1, and Day 45 = 1. IgA = Immunoglobulin A; IgG = Immunoglobulin G; Mdn = median; UL = upper limit; LL = lower limit.