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. 2022 Dec 6;13:7129. doi: 10.1038/s41467-022-34504-1

Table 3.

Results of linear regression models with Shannon index as the dependent variable

A. Model summary
R2 ΔR2 F change df1 df2 p
Unadjusted 0.0144 44.31 1 3033 <0.0001
Model 1 0.1568 0.1423 63.86 8 3025 <0.0001
Model 2 0.1720 0.0155 13.91 4 3021 <0.0001
Model 3 0.1831 0.0112 8.15 5 3016 <0.0001
B. Overview of coefficients
Dependent: Unadjusted Model 1 Model 2 Model 3
Shannon index B t p B t p B t p B t p
PHQ-9 (sum-score) −0.1200 −6.66 0.0000 −0.0664 −3.84 0.0001 −0.0544 −3.15 0.0016 −0.0388 −2.22 0.0263
Gender (Women = 1) 0.0839 4.95 0.0000 0.0721 4.06 0.0000 0.0740 4.18 0.0000
Age 0.0571 3.17 0.0015 0.0663 3.66 0.0003 0.0768 4.13 0.0000
Education 0.1089 5.64 0.0000 0.0913 4.70 0.0000 0.0850 4.39 0.0000
Smoker (Yes = 1) −0.0621 −3.52 0.0004 −0.0619 −3.52 0.0004
Physical activity (min/wk*intensity) 0.0078 0.46 0.6429 0.0064 0.38 0.7018
Audit alcohol (sum) −0.0555 −2.85 0.0044 −0.0545 −2.81 0.0050
BMI (kg/m2) −0.1036 −5.77 0.0000 −0.0995 −5.52 0.0000
GI disorder (yes = 1) −0.0318 −1.88 0.0600
Diabetes (yes = 1) −0.0408 −2.29 0.0219
Diarrhea (yes = 1) −0.0523 −3.12 0.0018
PPI (yes = 1) 0.0001 0.00 0.9976
Antibiotics (yes = 1) −0.0709 −4.29 0.0000

Tables present model summary (A) and overview of standardized regression coefficients (β) of predictor and covariates. Unstandardized values and constants are omitted for clarity. Models 1 to 3 also include ethnicity. Coefficients for ethnicity are reported separately in the text.