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. 2022 Dec 6;13:7507. doi: 10.1038/s41467-022-35217-1

Table 2.

Cancer occurrence among G2 men and women by G0 food access, restricted to G0s with rural childhoods: hazard ratios (HR)a and 95% confidence interval (95% CI) (Cox proportional hazard models) for total cancer, using intermediate food access as reference group

G2 men G2 women
Food access of Hazard Ratio 95% CI p value Hazard Ratio 95% CI p value
Paternal grandmother
 Good/abundant 1.08 0.54–2.12 0.808 0.97 0.64–1.47 0.875
 Poor/very poor 1.33 0.82–2.14 0.243 0.95 0.64–1.43 0.816
Paternal grandfather
 Good/abundant 3.05b 1.98–4.69 4.1E-07 1.14 0.82–1.59 0.443
 Poor/very poor 0.82 0.49–1.39 0.813 1.22 0.85–1.75 0.281
Person years 124,256 120,559
Cancer events 466 641
Maternal grandmother
 Good/abundant 0.89 0.58–1.37 0.596 0.9 0.69–1.38 0.886
 Poor/very poor 1.20 0.84–1.70 0.322 0.77 0.50–1.20 0.248
Maternal grandfather
 Good/ abundant 1.14 0.74–1.76 0.551 1.23 0.83–1.83 0.305
 Poor/ very poor 1.04 0.69–1.57 0.840 0.99 0.65–1.51 0.967
Person years 117 593 117 518
Cancer events 587 661

Bold figures: Estimated HR significantly higher than 1, two-tailed test.

aControlling for social and demographic factors, plus G0 partner’s and G1 parent food access

bGender interaction: p = 0.00002