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. 2022 Oct 19;127(12):2207–2219. doi: 10.1038/s41416-022-02011-1

Fig. 8. Histopathological analysis of rats treated with or without mTOR siRNA-loaded neutral liposome.

Fig. 8

H&E staining of vital organs (liver, heart, kidney, lungs, spleen and brain) tissues to determine biotoxicity isolated from animals belonging to different experimental groups (×400): Normal control: CTRL/SD/DMBA−/−, animals subjected to treatment with NL-C-siRNA: CTRL/SD/DMBA−/+ NL-C-siRNA, animals subjected to treatment with NL-mTOR-siRNA: CTRL/SD/DMBA−/+ NL-mTOR-siRNA. Scale bar represent 50 µm section. (H&E haematoxylin and eosin, NL-C-siRNA control siRNA-loaded neutral liposome, NL-mTOR-siRNA mTOR-siRNA-loaded neutral liposome, DMBA 7,12-dimethylbenz[a]anthracene, SD Sprague Dawley).