Table 2.

Parameter, description, value (unit), and references

Parameter	Description	Value (unit)	Reference
${\alpha }_T$	Glioma growth rate	1.575 (ml2 g−1 day−1)	[39, 40]
$K_T$	Glioma carrying capacity	2 (g ml−1)	[41]
$d_{\mathit{TI}}$	The degradation rate of glioma due to immune response	0.072 (day−1)	[5]
${\alpha }_{\mathit{TI}}$	The recruitment rate of the immune cell due to glioma	0.0003 (day−1)	[5]
$d_T$	The natural degradation rate of glioma	0.0001(day−1)	[42]
$d_I$	The natural degradation rate of immune cell	0.01 (day−1)	[5]
${\alpha }_s$	The recruitment rate of immune cell	0.7 (day−1)	[5]
$v$	Production rate of glioma	0.7 (day−1)	[5]
$d_{T\sigma }$	Glucose consumption rate by glioma	1 (day−1)	[5]
${\alpha }_{\sigma }$	The glucose transfer rate from serum to brain	20 (day−1)	[5]
$d_{\sigma 1}$	Glucose consumption of healthy cell	0.01 (g ml−1)	[43]
$d_{\sigma 2}$	Glucose consumption metabolism	0.00625 (g ml−1)	[43]
$d_{\mathit{TT}}$	Killing rate of glioma to immune cell	0.072 (g ml−1)	[43]
$K_T$	Killing rate of a chemotherapy agent for glioma	0.01 (day−1)	[44]
$k$	Rate of drug resistance	4.04 × 103 (mg−1)	[45]
$\beta$	Rate of virus infections	2 × 104 (ml g−1 day−1)	[46]
$s$	Rate of Immune cells stimulated by virus	0.15 (ml g−1 day−1)	[46]
$K_I$	Killing rate of a chemotherapy agent to immune cells	0.6 (day−1)	[13]
$d_{\mathit{ITi}}$	The natural death rate of immune cells responsible for the infection	0.1 (day−1)	[41]
$d_{\mathit{TiI}}$	The natural death rate of immune cell response to infection	4.8 × 10−2(ml g−1 day−1)	[42]
$I^N$	Normalized insulin concentrations	7.2	[43]
$G^N$	Normalized glucose concentrations	1.7647	[43]
$r_B$	The basal rate of glucose uptake	0.35 (g min−1)	[43]
$\mathit{PBF}$	Peripheral blood flow	900 (ml min−1)	[44]
$P(t)$	Injected chemotherapy agent	40–50 (mg kg−1)	[45]
$U(t)$	Injected virus	5 × 10−7 (g ml−1)	[46]
$d_Q$	The degradation rate of the chemotherapy agent	2.5 (day−1)	[45]
$b$	Burst size	150 × 10−6	[46]
$d_{\mathit{Ti}}$	The natural death rate of infected glioma	0.2 (day−1)	[46]
$\rho$	The loss rate of the virus during infection	4 × 10−2 (ml g−1 day−1)	[46]