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. 2022 Nov 23;13:1048180. doi: 10.3389/fmicb.2022.1048180

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Copyright © 2022 Chen, Wang, Zhang, Li, Gao, Nan, Zhao, Zhou and Liu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of viremia, fecal shedding, and seroconversion in SPF rabbits inoculated with different virus mixtures. (A–D) Rabbits inoculated with swine HEV mixed with nb14, nb53, nb anti-PCV2, and 1B5. (E,F) Rabbits inoculated with only CHN-SD-sHEV or PBS. Serum and fecal samples were collected before inoculation and weekly. ±, positive or negative HEV RNA in fecal or serum samples.