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. 2022 Oct 13;127(12):2108–2117. doi: 10.1038/s41416-022-02002-2

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© The Author(s), under exclusive licence to Springer Nature Limited 2022, Springer Nature or its licensor holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.

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Fig. 2 — a FACS-based evaluation of apoptosis rates of Panc-1 and Patu-8988 cells incubated with 200 μM Cory for 24 and 48 h or various concentrations of Cory (0, 200, and 400 μM) for 24 h. b TUNEL assay-based evaluation of apoptosis rates. Green, TUNEL; Blue, DAPI. Scale bar, 50 μm. Apoptosis index was expressed as the ratio of (TUNEL-positive cells)/(the number of nuclei) × 100%. c Protein expression levels of cleaved PARP and cleaved Caspase3 in the cells treated with 100 μM Cory for 24 or 48 h. The protein levels were normalised to GAPDH. Values were calculated based on three independent experiments and presented as mean ± SD. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001, compared with the control.