Skip to main content
. 2022 Nov 23;16:993019. doi: 10.3389/fncel.2022.993019

FIGURE 2.

FIGURE 2

Temporal changes in the mRNA expression level of inflammatory markers after contusive spinal cord injury. Real-time PCR quantification was used to evaluate the expression level of inflammatory-associated genes in the injured spinal cord at 1, 4, 7, and 28 days post-SCI. (A) SCI-induced pro-inflammatory activation genes included CD86, IL-12, IL-1β, and NF-κB. (B) Anti-inflammatory markers included CD206, IL-10, IL-13, and C/EBPβ which were downregulated following SCI. n = 3 for each group. One-way ANOVA with Dunnett multiple comparison tests was used to compare gene expression levels (*P< 0.05, **P< 0.01, ***P < 0.001). Data represented as mean ± SEM fold changes of gene expression.