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. 2022 Nov 23;9:922961. doi: 10.3389/fvets.2022.922961

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Copyright © 2022 Balamayooran, Atkins, Andrews, Michalson, Hutchison, LeGrande, Wilson, Gee, Aycock, Jorgensen, Young, Kock and Caudell.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Immunohistochemistry for myeloperoxidase (MPO)-positive neutrophils, vervets, multiple organs. (A) Y. enterocolitica-positive vervet, mesenteric lymph node, case 6. Neutrophils are present within the medullary sinus of a mesenteric lymph node adjacent to the affected colon. (B) Control vervet, mesenteric lymph node. Neutrophils are rarely observed within the control lymph node. (C) Y. enterocolitica-positive vervet, placenta, case 20. MPO-positive neutrophils are abundant within areas of placental necrosis. (D) Control vervet, placenta. Few neutrophils are present within the placenta, and often associated with physiologically normal areas of coagulative necrosis and mineral. (E) Y. enterocolitica-positive vervet, colon, case 3. MPO-positive neutrophils are prominent within mucosal lesions. Neutrophils are also present within veins and lymphatic vessels of the muscularis mucosa. (F) Control vervet, colon. Neutrophils within the control colon are rare and mainly within the lamina propria. (G) Y. enterocolitica-positive vervet, lung, case 1. Extravasated neutrophils are abundant within lesions of the lung. (H) Control vervet, lung. MPO-positive neutrophils are present only within blood vessels of the control lung.