. 2022 Nov 23;13:1062397. doi: 10.3389/fphys.2022.1062397

TABLE 3.

Linear regression models of physiological and self-reported hypoxia-related symptom frequency outcomes.

	Model 1				Model 2
	β	95% CI	p	R ²	β	95% CI	p	R ²
SpO₂ (%)				0.06				0.18
Sex ^a	−2.67	(−5.06, −0.29)	0.03−		−3.13	−5.42, −0.83)	0.01^**
Age	0.14	(−0.05, −0.29)	0.15		0.14	(−0.04, 0.33)	0.13
BMI	−0.31	(−0.45, 0.19)	0.42		−0.10	(−0.40, 0.20)	0.52
Altitude (k) ^b					−0.86	(−1.31, −0.42)	0.01^**
Exposure (min) ^c					−0.18	(−0.35, −0.01)	0.04−
HR (bpm)				0.08				0.11
Sex	1.16	(−4.08, 6.39)	0.66		1.50	(−3.80, 6.81)	0.58
Age ^d	−0.69	(−1.12, −0.26)	0.01^**		−0.69	(−1.12, −0.26)	0.01^**
BMI	0.01	(−0.69, 0.72)	0.97		−0.02	(−0.72, 0.68)	0.96
Altitude (k)					0.18	(−0.09, 1.97)	0.07
Exposure (min)					0.15	(−0.25, 0.55)	0.46
Hypoxia-related symptomfrequency score (n)				0.01				0.22
Sex	0.58	(−0.45, 1.62)	0.27		0.61	(−0.33, 15.6)	0.20
Age	0.02	(−0.06, 0.11)	0.59		0.03	(−0.05, 0.10)	0.51
BMI	0.01	(−0.13, 0.15)	0.91		0.00	(−0.12, 0.13)	0.99
Altitude (k) ^e					0.47	(0.28, 0.65)	0.01^**
Exposure (min)					0.01	(−0.06, 0.08)	0.73

Note. Abbreviations (β = beta; CI, confidence interval; R ² = variance explained; SpO₂ = peripheral capillary oxygen saturation; BMI, body mass index; HR, heart rate; ERPs, event-related potentials). Male reference value for sex. SpO₂ and heart absolute change between normoxia and hypoxia exposures.

^{^a}

Female sex significantly predicted decreased SpO_2, p = .01.

^{^b}

Altitude significantly predicted decreased SpO₂, p < .001.

^{^c}

Exposure minutes significantly predicted decreased SpO₂, p = .04.

^{^d}

Age significantly predicted decreased HR, p = .01.

^{^e}

Altitude significantly predicted increased hypoxia-related symptom frequency scores, p < .001. ^** p < .01. ^* p < .05.