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. 2022 Dec 6;12:21104. doi: 10.1038/s41598-022-25436-3

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Microbiota variation between healthy subjects and acne patients. Skin microbiota was evaluated on samples collected from the skin of ten healthy subjects (HS) and non-inflammatory (NI) and inflammatory lesions (AL) of 10 acne patients. Relative abundances at the phylum level (a) and top eight genera (b) were represented in a stacked bar plot. (c). Relative abundance was evaluated at the species level for Cutibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis relative abundances. Significance was assessed by using the Kruskal Wallis static test. *, P < 0.05; **, P < 0.01; ***, P < 0.001, ****, P < 0.0001.