Table 2.
Clinical characteristics and treatments in patients with moderate to severe UC exacerbations.
| Characteristics | Overall exacerbations | Initial exacerbations | Relapse exacerbations |
|---|---|---|---|
| (n = 959) | (n = 525) | (n = 266) | |
| Age, year, mean (SD) | 38.6 (17.4) | 38.1 (17.9) | 38.3 (16.9) |
| Partial Mayo, severe (n [%]) | 246 (25.6) | 155 (29.5) | 59 (22.2) |
| Pancolitis UC (n [%]) | 403 (42.0) | 210 (40.0) | 115 (43.2) |
| Laboratory data, mean (SD) | |||
| White blood cell | 8924.8 (3769.8) | 9201.2 (3891.9) | 8736.7 (3637.8) |
| Serum albumin | 3.76 (0.71) | 3.61 (0.79) | 3.99 (0.532) |
| C-reactive protein | 2.70 (4.36) | 3.23 (4.83) | 2.06 (3.42) |
| Hospitalization (n [%]) | 372 (38.8) | 236 (45.0) | 85 (31.7) |
| Treatments for exacerbations (n [%]) | |||
| 5-ASAs | 330 (34.4) | 292 (55.6) | 29 (10.9) |
| Single-use | 124 (12.9) | 106 (20.2) | 15 (5.6) |
| Corticosteroids | 628 (65.5) | 342 (65.1) | 179 (67.2) |
| Immunomodulators | 78 (8.1) | 39 (7.4) | 20 (7.5) |
| Calcineurin inhibitors | 204 (21.3) | 110 (21.0) | 61 (22.9) |
| Biologics | 164 (17.1) | 55 (10.5) | 41 (15.4) |
| Apheresis | 254 (26.5) | 133 (25.3) | 78 (29.3) |
| Surgical resection | 81 (8.4) | 42 (8.0) | 22 (8.3) |