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. 2022 Dec 6;12:21100. doi: 10.1038/s41598-022-25186-2

Table 1.

Clinical characteristics of enrolled patients.

HFS (n = 36) WPS (n = 20) WFS (n = 28) p-value
Age, years 72 (36–86) 69.5 (55–94) 66.5 (46–82) 0.280
Male gender 19 (52.8) 13 (46.4) 11 (55.0) 0.816
Bilirubin level, mg/dl 2.5 (0.8–12.8) 3.1 (0.9–20.2) 4.1 (0.8–32.0) 0.274
Alkaline phosphatase level, U/L 382.5 (156–2089) 370 (187–953) 307 (167–1710) 0.265
Gallbladder stones / sludge 3 (8.3) 2 (10.0) 5 (17.9) 0.484
Ascites 11 (30.6) 0 (0) 5 (17.9) 0.020
Tumor involvement to the orifice of cystic duct 2 (5.6) 0 (0) 3 (10.7) 0.300
Duodenal invasion 15 (41.7) 9 (45.0) 8 (28.6) 0.433
Duodenal stent placement 8 (22.2) 5 (25.0) 5 (17.9) 0.829
Prior biliary drainage before SEMS placement 25 (69.4) 10 (50.0) 18 (64.3) 0.348
Sphincterotomy before SEMS placement 30 (83.3) 4 (20.0) 22 (78.6)  < 0.001
Length of the stricture, mm 23 (12–50) 23 (10–36) 23 (11–37) 0.691
Diameter of the dilated bile duct, mm 11.9 (6.6–21.0) 12.4 (8.5–17.1) 12.1 (7.6–21.0) 0.497
The length of SEMS; 4 cm / 6 cm / 8 cm 0 (0) / 31 (86.1) / 5 (13.9) 3 (15.0) / 14 (70.0) / 3 (15.0) 4 (14.3) / 23 (82.1) / 1 (3.6) 0.104
Anti-cancer treatment after SEMS placement 30 (83.3) 18 (90.0) 28 (100) 0.079
Median survival time after SEMS placement, (range), days 251 (44–751) 243 (31–930) 298 (24–1032) 0.785

Data are presented as median (range) or number (proportion).

SEMS Self-expandable metal stent, HFS HILZO fully covered stent, WPS WALLFLEX biliary RX partially covered stent, WFS WALLFLEX biliary RX fully covered stent.