Table 3.
Odds ratios for frailty by logistic regression analyses.
| Variables | Univariable OR | Multivariable OR (Model 1) | Multivariable OR (Model 2) | Multivariable OR (Model 3) | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR | (95% CI) | p-value | OR | (95% CI) | p-value | OR | (95% CI) | p-value | OR | (95% CI) | p-value | |
| Age (years) | 1.06 | (1.04–1.08) | < 0.001 | 1.05 | (1.03–1.07) | < 0.001 | 1.04 | (1.02–1.06) | < 0.001 | 1.05 | (1.03–1.07) | < 0.001 |
| Duration of disease (years) | 1.02 | (1.00–1.04) | 0.025 | – | – | – | ||||||
| BMI (kg/m2) | 1.03 | (0.98–1.08) | 0.280 | 1.07 | (1.00–1.14) | 0.046 | 1.07 | (1.01–1.14) | 0.027 | 1.08 | (1.01–1.14) | 0.016 |
| Married | 0.60 | (0.40–0.88) | 0.010 | – | – | – | ||||||
| Education ≥ 13 years | 0.61 | (0.39–0.93) | 0.023 | – | – | – | ||||||
| Steinbrocker stage (3/4) | 1.62 | (1.09–2.40) | 0.017 | – | – | – | ||||||
| Diabetes mellitus | 2.31 | (1.09–4.88) | 0.029 | – | – | |||||||
| Hypertension | 2.63 | (1.58–4.35) | < 0.001 | – | – | |||||||
| Osteoporosis | 2.80 | (1.83–4.28) | < 0.001 | – | – | |||||||
| Ever or current malignancy | 2.24 | (1.09–4.64) | 0.029 | – | – | |||||||
| DAS28-CRP | 1.91 | (1.54–2.35) | < 0.001 | 1.74 | (1.34–2.26) | < 0.001 | ||||||
| Finger/wrist joint symptoms | 1.71 | (1.14–2.55) | 0.009 | – | 1.64 | (1.01–2.65) | 0.044 | |||||
| Grip strength (kg) | 0.89 | (0.86–0.92) | < 0.001 | 0.93 | (0.89–0.97) | < 0.001 | 0.90 | (0.87–0.94) | < 0.001 | 0.90 | (0.86–0.94) | < 0.001 |
Frailty, The Kihon Checklist (KCL) ≥ 8 points.
OR odds ratio, CI confidence interval, BMI body mass index, DAS28-CRP 28-joint count Disease Activity Score using C-reactive protein.