Table 1.
Comparison of clinicopathologic variables between negative and positive groups.
| Variable | Serum calcitonin level | p | |
|---|---|---|---|
| Positive (n = 288) | Negative (n = 24) | ||
| Age | |||
| ≤50 | 149 | 12 | |
| >50 | 139 | 12 | 0.870 |
| Sex | |||
| Male | 69 | 4 | |
| Female | 219 | 20 | 0.418 |
| Tumor size (mm) | |||
| ≤10 | 78 | 8 | |
| >10 | 210 | 16 | 0.510 |
| Serum Carcino-Embryonic Antigen level | |||
| Normal | 8 | 22 | |
| Elevated | 280 | 2 | <0.001 |
| RET gene mutation^ | |||
| Yes | 6 | 0 | |
| No | 105 | 24 | 0.370 |
| Foci | |||
| Single | 268 | 24 | |
| Multiple | 20 | 0 | 0.248 |
| MTC* type | |||
| Sporadic | 287 | 24 | |
| Familial | 1 | 0 | 1.000 |
| Con occurrence | |||
| PTC& | 30 | 0 | |
| No | 258 | 24 | 0.146 |
| Lymph node metastasis | |||
| Yes | 138 | 0 | |
| No | 150 | 24 | <0.001 |
| Operation type! | |||
| TT+CLND | 200 | 7 | |
| TT+CLND+LLND | 88 | 0 | |
| UL+CLND | 0 | 17 | <0.001 |
*MTC, Medullary thyroid carcinoma;
^Status of RET gene mutation in 177 patients was unknown;
&PTC, Papillary thyroid carcinoma;
!TT, total thyroidectomy; CLND, central lymph node dissection; LLND, lateral lymph node dissection; UL, unilateral lobectomy.