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. 2022 Nov 23;13:1052644. doi: 10.3389/fphar.2022.1052644

FIGURE 2.

FIGURE 2

MDP inhibits inflammatory response in the intestine. (A) Representative images of H&E staining for terminal ileum and colon tissues in PBS, MDP, DSS + PBS, and DSS + MDP group mice (n = 6, each group), respectively. scale bars: 50 μm. (B) Quantification of villus height, crypt depth, and the ratio of villus height and crypt depth in the terminal ileum (n = 6, each group). (C) The histological score of colons (n = 6, each group). (D) Western blotting analysis for TNF-α and Cleaved caspase 3 with β-Actin as the internal standard protein in colon of PBS, MDP, DSS + PBS, and DSS + MDP group mice. Representative images of three duplicate samples of the immune blotting were shown. (E,F) Quantification of the relative expression of TNF-α and Cleaved caspase 3 in panel (D) by ImageJ, respectively. Data were expressed as mean ± SEM. *p <0.05, **p <0.01, ***p <0.001, ****p <0.0001, ns, not significant, One-way ANOVA.