FIGURE 4.

MDP decreases the apoptosis of intestinal epithelium in DSS-induced mice. (A) Representative images of TUNEL staining for terminal ileum and colon tissues in PBS, MDP, DSS + PBS, and DSS + MDP group mice (n = 3, each group), respectively. scale bars: 50 μm. Red arrows indicated positive cells. (B,C) Quantification of TUNEL positive cells per mm² in terminal ileum and colon (n = 3, each group), respectively. (D) Representative images of Ki67 staining for terminal ileum and colon tissues in PBS, MDP, DSS + PBS, and DSS + MDP group mice (n = 3, each group), respectively. scale bars: 50 μm. Red arrows indicated positive cells. (E,F) Quantification of Ki67 positive cells per mm² in terminal ileum and colon (n = 3, each group), respectively. Data were expressed as mean ± SEM. ***p <0.001, ****p <0.0001, ns, not significant, One-way ANOVA.