Skip to main content
. 2022 Dec 6;12:21109. doi: 10.1038/s41598-022-25540-4

Table 2.

Hazard ratios (HRs) and 95% confidence intervals (CIs) for recurrence-free survival (RFS).

Univariate analysis Multivariate analysis
HRs (95% CIs) p value HRs (95% CIs) p value
Age (continuous) 1.007 (0.957–1.059) 0.785 N/A
BMI (continuous) 1.047 (0.920–1.191) 0.490 N/A
ER 0.239 N/A
 Negative 1
 Positive 0.574 (0.228–1.446)
PR 0.102 N/A
 Negative 1
 Positive 0.454 (0.176–1.171)
HER2 0.704 N/A
 Negative 1
 Positive 0.806 (0.265–2.450)
HG 0.864 N/A
 I, II 1
 III 1.044 (0.637–1.711)
Tumor size 0.228 N/A
  ≤ 2 cm 1
  > 2 cm 1.766 (0.701–4.450)
Lymph node metastasis 0.037 0.597
 Negative 1 1
 Positive 2.689 (1.061–6.815) 1.404 (0.398–4.954)
AJCC stage 0.040 0.079
 I 1 1
 II 3.745 (1.192–11.764) 3.197 (1.015–10.072)
 III 3.534 (0.791–15.798) 3.337 (0.745–14.935)
Lymphovascular invasion 0.820 N/A
 Negative 1
 Positive 0.864 (0.246–3.039)
SUVmean-VAT 0.041 0.023
 Low 1 1
 High 2.928 (1.043–8.215) 3.361 (1.181–9.566)
Chemotherapy 0.543 N/A
 Not done 1
 Done 0.745 (0.289–1.922)
Radiotherapy 0.969 N/A
 Not done 1
 Done 0.982 (0.387–2.491)
Endocrine therapy 0.021 0.014
 Not done 1 1
 Done 0.329 (0.127–0.848) 0.300 (0.115–0.786)

BMI Body mass index; ER Estrogen receptor; PR Progesterone receptor; HER2 Human epidermal growth factor receptor 2; HG Histologic grade; VAT Visceral adipose tissue; N/A Not assessed.