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. 2022 Nov 23;12:1012889. doi: 10.3389/fonc.2022.1012889

Table 1.

Baseline characteristics of RI and no-RI patients.

Characteristics RI no-RI p-value
age (x ± s) 60 ± 11 56 ± 11 0.081
male/female 34/13 19/19 0.035
hypertension no 24 31
yes 23 7 0.003
diabetes no 42 35
yes 5 3 0.954
bone lesion 24 (55.8%) 22 (68.7%) 0.391
M protein (g/L) 4.75 (1.96, 13.78) 5.62 (2.27, 17.18) 0.854
WBC>9.5 (1012/L) 6 (12.8%) 1 (2.6%) 0.124
Hb <100 (g/L) no 12 16
yes 35 22 0.106
Ca>2.7 (mmol/L) 8 (17%) 4 (10.5%) 0.393
UA (μmol/L) 508.94 ± 242.92 375.16 ± 142.05 <0.001
Scr (μmol/L) 562.33 ± 254.94 91.86 ± 31.71 <0.001
TG>1.7 (mmol/L) 20 (45.5%) 9 (26.5%) 0.085
ALB<35 (g/L) 11 (24.3%) 0 (0%) 0.001
β2-MG>8 (mg/L) 35 (89.7%) 7 (18.9%) <0.001
LDH>245 (U/L) 26 (60.5%) 11 (32.4%) 0.014
triple hit 35 (100%) 29 (100%) >0.999
κ-λ (mg/L) 4165.80 (708.80, 8930.80) 2707.00 (254.15, 4385.07) 0.002

BM, bone marrow; M protein, blood M protein content; WBC, white blood cell; Hb, hemoglobin; Ca, serum calcium; UA, uric acid; TG: triglyceride; ALB, albumin; β2-MG, β2-microglobulin; LDH, lactate dehydrogenase; triple hit, serum protein electrophoresis showed that IgA, IgG, and IgM decreased; free λ, serum dissociation λ light chain; κ-λ, serum dissociation κ light chain and λ light chain difference; Scr, serum creatinine.