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. 2022 Nov 23;13:1049188. doi: 10.3389/fimmu.2022.1049188

Table 1.

Epidemiologic and clinical features in our cohort of young-adult liver transplanted patients.

Characteristics Young-adult liver transplanted patients (n=33)
Male/Female, n 20/13
Original disease, n
Biliary atresia
Re-transplanted biliary atresia
Alagille syndrome
Metabolic disorders (MSUD, PA, OTCD)
LKM-positive autoimmune hepatitis
Hepatoblastoma
Alpha-1 antitrypsin deficiency
Congenital hepatic fibrosis
Acute liver failure
Cirrhosis

14
5
3
3

1

1
2
1
2
1
Post-transplant time, years 10.2 ± 5.6 (0.12-18.7)
Tacrolimus based immunosuppression, n 30
Tacrolimus blood levels, ng/ml 4.3 ± 1.4
Treatment combinations, n
Tacrolimus
Pred + Tacrolimus
Pred + Tacrolimus + MMF
Pred
Pred + Cyclosporine

4
20
6
1
2
Dysfunctional/Normal graft, n 8/25
Median ALT, U/L 28

ALT, Alanine aminotransferase; MMF, mycophenolate mofetil; MSUD, Maple syrup urine disease; OTCD, Ornithine transcarbamylase deficiency; PA, Propionic academia; Pred, low dose methylprednisolone.