Table 1.
Epidemiologic and clinical features in our cohort of young-adult liver transplanted patients.
| Characteristics | Young-adult liver transplanted patients (n=33) |
|---|---|
| Male/Female, n | 20/13 |
|
Original disease, n
Biliary atresia Re-transplanted biliary atresia Alagille syndrome Metabolic disorders (MSUD, PA, OTCD) LKM-positive autoimmune hepatitis Hepatoblastoma Alpha-1 antitrypsin deficiency Congenital hepatic fibrosis Acute liver failure Cirrhosis |
14 5 3 3 1 1 2 1 2 1 |
| Post-transplant time, years | 10.2 ± 5.6 (0.12-18.7) |
| Tacrolimus based immunosuppression, n | 30 |
| Tacrolimus blood levels, ng/ml | 4.3 ± 1.4 |
|
Treatment combinations, n
Tacrolimus Pred + Tacrolimus Pred + Tacrolimus + MMF Pred Pred + Cyclosporine |
4 20 6 1 2 |
| Dysfunctional/Normal graft, n | 8/25 |
| Median ALT, U/L | 28 |
ALT, Alanine aminotransferase; MMF, mycophenolate mofetil; MSUD, Maple syrup urine disease; OTCD, Ornithine transcarbamylase deficiency; PA, Propionic academia; Pred, low dose methylprednisolone.