TABLE 3.

Effect of gestational chronodisruption and melatonin supplementation on gestation length, maternal weight gain, and newborn variables.

	LD (n = 5)&	CPS (n = 7)#	CPS + Mel (n = 5)
Gestation length (days)	21.64 ± 0.03	22.12 ± 0.10*	22.03 ± 0.02
Maternal weight gain (g)	131.0 ± 10.2	126.0 ± 6.2	155.50 ± 7.90
Liter size (number)	13.20 ± 1.0	13.80 ± 0.97	15.5 ± 0.80
Newborn body weight (g)	6.50 ± 0.10	7.38 ± 0.10*	7.28 ± 0.22
Sex distribution (M/F)	28/32	45/51	30/32

LD, mothers under light-dark cycle 12/12; CPS, mothers under chronic photoperiod shift throughout gestation; GW, gestational week; SEM, standard error of the mean. *Different from LD (P < 0.001, unpaired t-test). ^&Data from LD mothers has already been published (Mendez et al., 2016).

^#Here we include data from CPS (n = 4) that has already been published (Mendez et al., 2016) plus three animals to complete n = 7.