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. 2022 Nov 23;12:949111. doi: 10.3389/fonc.2022.949111

Table 2.

Prediction performance of model 1-5.

Cohort Model AUC (95%CI) SEN SPE ACC PPV NPV AIC
Training cohort Model 1 0.84(0.75-0.93) 0.78 0.83 0.80 0.93 0.66 88.87
Model 2 0.79(0.69-0.89) 0.66 0.83 0.72 0.88 0.65 90.81
Model 3 0.84(0.75-0.93) 0.80 0.80 0.79 0.88 0.66 83.36
Model 4 0.92(0.86-0.98) 0.93 0.83 0.90 0.91 0.86 64.06
Model 5 0.93(0.88-0.98) 0.96 0.76 0.90 0.89 0.92 60.14
Validation cohort Model 1 0.87 (0.77-0.98) 0.66 1.00 0.82 1.00 0.63
Model 2 0.78 (0.63-0.93) 0.81 0.66 0.76 0.84 0.61
Model 3 0.80(0.64-0.95) 0.85 0.66 0.79 0.85 0.66
Model 4 0.90(0.81-0.99) 0.81 1.00 0.87 1.00 0.70
Model 5 0.91(0.81-0.99) 0.70 1.00 0.79 1.00 0.60

AUC, area under the curve; CI, confidence interval; SEN, sensitivity; SPE, specificity; ACC, accuracy; PPV, positive predictive value; NPV, negative predictive value; AIC, Akaike information criterion.