. 2022 Nov 23;13:1055765. doi: 10.3389/fphar.2022.1055765

TABLE 2.

Effect of the Dihydro-p-coumaric acid on body weight, food intake and water intake on BALB/c mice in sub-acute toxicity study.

	Female					Male
	Initial weight	Day 7 (g)	Day 14 (g)	Food intake (g/day/mice)	Water intake (ml/day/mice)	Initial weight	Day 7 (g)	Day 14 (g)	Food intake (g/day/mice)	Water intake (ml/day/mice)
Control	19.18 ± 0.31^b	18.62 ± 0.87^a	21.34 ± 0.35^b	2.54 ± 0.13^a	3.69 ± 0.09^c	16.10 ± 0.88^a	16.82 ± 0.92^a	17.94 ± 0.70^a	2.82 ± 0.49^a	4.03 ± 0.06^c
50 mg/kg bw	18.36 ± 0.74^a	19.48 ± 0.69^b	20.24 ± 0.64^a	2.50 ± 0.08^a	2.81 ± 0.02^a	17.08 ± 0.47^b	17.62 ± 0.42^a	18.48 ± 0.40^a	3.68 ± 0.40^b	3.69 ± 0.09^b
500 mg/kg bw	19.32 ± 0.52^a	20.04 ± 0.28^b	20.86 ± 0.33^a	2.51 ± 0.06^a	2.94 ± 0.16^a	16.54 ± 0.68^a	18.76 ± 0.05^b	17.72 ± 0.73^a	2.98 ± 0.24^a	3.42 ± 0.13^a

Values are expressed as mean ± SEM (df = 4) followed by the same letter of the alphabet (a, b) do not differ significantly each other (ANOVA, Tukey test post-hoc, p > 0.05).