Table 3.
Multivariate analysis examining for variables associated with increased likelihood of local failure in patients with ≥3 contiguous treated levels using a proportional hazards model.
| Variable | Hazard Ratio | 95% Confidence Interval | p-value |
|---|---|---|---|
| Age | 0.993 | 0.089–1.107 | 0.894 |
| Gender | 0.884 | 0.088–8.909 | 0.917 |
| Surgery vs Definitive | 8.652 | 0.634–118.000 | 0.106 |
| Prescribed dose (BED) | 1.372 | 0.269–7.000 | 0.704 |
| Minimum dose (BED) | 0.87 | 0.689–1.098 | 0.24 |
| Mean dose (BED) | 1.816 | 0.411–8.000 | 0.431 |
| D90% (BED) | 0.186 | 0.005–6.892 | 0.361 |
| D95% (BED) | 3.653 | 0.313–42.600 | 0.302 |
| Treatment volume | 1.011 | 1.001–1.021 | 0.025 |
| Histopathology | 0.85 | 0.600–1.200 | 0.395 |
| SINS | 0.543 | 0.207–1.430 | 0.216 |
| Bilsky | 0.022 | 0.001–3.600 | 0.143 |
| Systemic disease status | 27 | 1.700–428.000 | 0.019 |
BED, biologically effective dose. The bold values: statistically significant values.