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. 2022 Nov 23;13:1062026. doi: 10.3389/fphar.2022.1062026

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Copyright © 2022 Shi, Ruan, Zhong, Teng, Ke and Yao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(A) Represents the SDS-PAGE analysis for the total proteins of C, M, HSYA and SYR group. (B,C) show the PCA analysis score plot and the difference proteins numbers, respectively for M vs. C, HSYA vs. M and SYR vs. M groups. (D–F) show the difference expression proteins location in the comparisons for M vs. C, HSYA vs. M and SYR vs. M groups, respectively. (G–I) show the GO annotation results of the difference expression proteins for M vs. C, HSYA vs. M and SYR vs. M groups, respectively. (J–L) show the downregulation and upregulation pathways for M vs. C, HSYA vs. M and SYR vs. M groups, respectively.