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(A) Venn diagram of PK marker identification for SI and (B) the integrated drug plasma concentration-time curves by the effect weighting integrated method with the plasma concentration of two ingredients HSYA and SYR after i.v., administration of SI with high (4 ml/kg, Mean ± SD, n = 3), medium (2 ml/kg, Mean ± SD, n = 3), and low (1 ml/kg, Mean ± SD, n = 4) dosages.
