Table 3.

Multivariate analysis of PFS and OS in patients with NSCLC.

Characteristics	PFS		OS
	HR (95%CI)	P-value	HR (95%CI)	P-value
ECOG PS (<2/≥2)	6.947 (3.657-13.194)	<0.001*	–	–
Smoking history	4.076 (2.238-7.427)	<0.001*	14.003 (2.038-96.204)	0.007*
No. of metastases (0/≤2/≥3)	1.356 (1.040-1.769)	0.024*	–	–
Line of Apatinib (Second line/Further line)	–	–	0.219 (0.057-0.846)	0.028*
Short-term efficacy (PR/SD/PD)	2.188 (1.483-3.226)	<0.001*	–	–

PFS, progression-free survival; OS, overall survival; HR, hazard ratio; CI, confidence interval; ECOG PS, Eastern Cooperative Oncology Group performance status; PR, partial response; SD, stable disease; PD, progressive disease.

*Statistically significant values, P <0.05.