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. 2022 Nov 23;13:1060104. doi: 10.3389/fphar.2022.1060104

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Copyright © 2022 Li, Yang, Li, Wang, Liu, Chen and Diao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Cor inhibited NLRP3 inflammasome activation and alleviated pyroptosis in mice. (A) The protein expression levels of NLRP3, caspase 1 P20, and GSDMD-NT in intestine tissue. (B) The effects of Cor on LDH level in intestine tissue. (C) The protein expression levels of NLRP3, ASC, caspase 1 P20, and GSDMD-NT in lung tissue. (D) The effects of Cor on LDH level in lung tissue. Data are expressed as the mean ± SEM (n ≥ 3), ^# p < 0.05 and ^## p < 0.01 vs. sham group, *p < 0.05 and **p < 0.01 vs. II/R group.